Malignant Tumors of the Larynx: A Clinicopathological Study of 30 Cases

Abstract Background:Cancer of the larynx is a common cancer of the head and neck. This cancer has an established correlation with smoking tobacco and alcohol as causative agents. This study has been conducted in a tertiary hospital in Northeastern India. Minimal data about laryngeal cancer from this area was published in the literature. Methods: This prospective study was conducted for a period of two years and enrolled 30 patients. Patients were diagnosed, staged, and treated for the cancer, then followed for 12 months. Results: This study showed that patients in the sixth decade of life were the most common patients that presented with this cancer. There was a male preponderance. Smoking and alcoholism were the most common associated risk factors. Most patients presented with hoarseness followed by a foreign body sensation in the throat. The majority presented with late stage disease. The most common larynx tumor in this study was glottic carcinoma. All cases were squamous cell carcinoma and most were moderately differentiated. Patients underwent treatment with radiation therapy and chemotherapy. Conclusion: At the one year follow up, 36.67% of patients were found to be in remission. A total of two patients succumbed to this disease.